The day rule was put in place ostensibly in order to avoid causing pain for the developing embryo. The primitive streak — the first visible evidence of gastrulation and the formation of differentiated tissues in the embryo — appears at about day 15 after fertilization. See video at the bottom of this post for more information. When the day rule was put in place, laboratories were not able to maintain embryos beyond a few days, so 14 days was an acceptable limit to the decision-makers involved. Recent developments, however, have changed the research landscape, and arguments about changing the day rule are being put forward. What would happen if you could treat human pluripotent stem cells hPSCs in such a way that they developed into an entity that resembled an embryo that is further along than 14 days? Would the day rule apply? The situation can be described figuratively by saying that current guidelines look at development as a single long highway, so that boundaries that address moral concerns can be set by erecting a stop sign at a suitable place.


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To save this word, you'll need to log in. Trump directed an aide to bring him a sheaf of news clippings, reminisced at length about his victory, criticized windmills and provided xenophobic pop culture commentary. Send us feedback. See more words from the same century Dictionary Entries near sheaf shea butter shea butter tree sheading sheaf sheaf arrow sheaf catalog sheafy. Accessed 25 Aug.
Sheef Sentence Examples
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